megatomi.com Secrets
megatomi.com Secrets
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Speedily get sections as slim or thick as your software demands, devoid of stressing about losing or distorting beneficial tissue samples.
Megatome is actually a vibrating microtome designed to segment a broad variety of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With significant blade vibrating frequency and minimized blade deflection, Megatome permits superior-throughput tissue sectioning with uniform surface profile, in addition to minimum tissue damage and data reduction.
Antibodies could get weeks to diffuse by only some millimeters of tissue, which has a steep labeling gradient from area to Main.
Megatome is suitable for precision: the blade vibrates at an increased frequency and bigger amplitude selection than other microtomes, and incorporates a exclusive deflection Management mechanism.
SE utilizes a rotational electric area to disperse highly electromobile molecules (such as antibodies or surfactant micelles) all over a porous sample without detrimental electrically charged constructions within the tissue. This enables two-four working day clearing of intact organs,
Our preformulated EasyIndex solution raises and homogenize the refractive index of delipidated tissue samples, rendering them absolutely clear. This permits light penetration into your sample and makes certain the acquisition of large-resolution, in-concentrate image facts.
It is best to only must set the javadocTask residence once the endeavor you utilize to produce Javadoc is non-standard. One example is, there may be a task identified as allJavadoc in a multi-module
eFLASH is a quick tissue labeling procedure which allows for uniform megatomi.com complete-organ staining in twenty rounds of labeling.
The SmartSPIM light sheet microscope presents unparalleled resolution and acquisition pace all through intact tissue volumes, though its modular layout permits you to enhance and personalize person factors.
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Defend avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, guarding specimens for a number of rounds of processing.
Leverage the Very clear+ tissue clearing strategy, along with eFLASH and patented stochastic electrotransport technologies, to quickly very clear and label complete organs. Critical highlights and options involve:
Our novel Protect tissue preservation procedure varieties intramolecular bonds employing polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.